A serial site – in Cape Province, South Africa – made up of eight protected areas, covering 553,000 ha, the Cape Floral Region is one of the richest areas for plants in the world. It represents less than 0.5% of the area of Africa but is home to nearly 20% of the continent’s flora. The site displays outstanding ecological and biological processes associated with the Fynbos vegetation, which is unique to the Cape Floral Region. The outstanding diversity, density and endemism of the flora are among the highest worldwide. Unique plant reproductive strategies, adaptive to fire, patterns of seed dispersal by insects, as well as patterns of endemism and adaptive radiation found in the flora, are of outstanding value to science.